In silico ADME/T modelling for rational drug design

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In silico ADME/T modelling for rational drug design.

In recent decades, in silico absorption, distribution, metabolism, excretion (ADME), and toxicity (T) modelling as a tool for rational drug design has received considerable attention from pharmaceutical scientists, and various ADME/T-related prediction models have been reported. The high-throughput and low-cost nature of these models permits a more streamlined drug development process in which ...

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ژورنال

عنوان ژورنال: Quarterly Reviews of Biophysics

سال: 2015

ISSN: 0033-5835,1469-8994

DOI: 10.1017/s0033583515000190